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4°C, protect from light
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
20137-37-5
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥538.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥233.0 |
| 规格： | 5 mg | 产品价格： | ￥500.0 |
| 规格： | 10 mg | 产品价格： | ￥700.0 |
| 规格： | 25 mg | 产品价格： | ￥1200.0 |
| 规格： | 50 mg | 产品价格： | ￥1650.0 |
| 规格： | 100 mg | 产品价格： | ￥2475.0 |
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Rotundic acid
CAS No. : 20137-37-5
MCE 国际站：Rotundic acid
产品活性：Rotundic acid 是一种从铁冬青 (Ilex rotunda Thunb) 中获得的三萜类化合物，可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。Rotundic acid 具有抗炎和保护心脏的能力。
研究领域：PI3K/Akt/mTOR | MAPK/ERK Pathway | Apoptosis
作用靶点：Akt | mTOR | p38 MAPK | Apoptosis
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文献和实验。 14B、随后将新的类器官转移至 1.5ml 离心管中，高速（约 6000g）离心 3-5s，或低速（约 300g）离心 3min。离心后，上皮碎片将沉降到底部，Matrigel 继续悬浮在培养基中，细胞团沉积在离心管底部。 15B、在显微镜下用移液器取出培养基和 Matrigel，向沉淀的细胞团内添加 200μl 新鲜的 Matrigel，混合均匀后在 24 孔板的每个培养孔中心接种 25μl 混合液。待 Matrigel 在 37℃ 培养箱中静置 10min 凝固后，加入 0.5ml 人芽尖
0,02% sodium thiosulfate for 1 min.5)Rinse with water for 1 min.2X.0.02% Sodium Thiosulfate: For 1 gel,add 30mg sodium thiosulfate-5 hydrate to 150ml water.Silver reaction6)Submerge gel in 150ml 0.1% silver nitrate with 0.08% formalin (37%)for 20 min
Communications【4-5】和 Cells【6】发表的三篇文章，整理了人多能干细胞（hPSC）来源的胰岛样类器官培养方案。该培养过程遵循发育原理，由 hPSC 依次分化为定型内胚层 （DE）、胰腺祖细胞 （PP）、内分泌前体 （EP）， 最终诱导发育为人胰岛样类器官（human Islet-like Organoid, hILO）。 图 1. hPSC 来源细胞诱导成为胰岛样类器官的培养方案示意图【7】 细胞来源 hPSC 培养试剂配方 包被液 hPSC培养基 Day1 Day
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