AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.
克隆类型:
Mouse Monoclonal Antibody
亚型:
Mouse IgG1
免疫原:
Purified recombinant fragment of human AAT expressed in E. coli.
适用物种:
H, M
应用范围:
WB
应用说明:
E: 1:10000; WB: 1:500-1:2000
别名:
Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; SERPINA1; AAT; PI
形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
保存条件:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.