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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABAA receptor alpha 2.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
M, R, B, D, H, Mk, Zf
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABAA receptor alpha 2.
- 目录编号:
253141
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
GABAA Receptor alpha-2
- 抗体英文名:
GABAA Receptor alpha-2 Antibody
- 抗体名:
GABAA Receptor alpha-2 Antibody
- 规格:
0.1 ml
GABAA Receptor alpha-2 Antibody产品详细介绍:
| 产品名称: | GABAA Receptor alpha-2 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253141 |
| 规格: | 0.1 ml |
| 产品描述: | Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a chloride channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABAA receptor alpha 2. |
| 适用物种: | M, R, B, D, H, Mk, Zf |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:1,000 |
| 别名: | Gamma-aminobutyric acid receptor subunit alpha-2; GABA(A) receptor subunit alpha-2; Gabra2; Gabra-2 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Synaptoneurosomes: A Preparation for Studying Subhippocampal GABAA Receptor Activity
by postsynaptic mechanisms. In the past, isolated membrane fractions enriched in postsynaptic densities have been used for this purpose (1 ). However, this fraction of postsynaptic densities is not appropriate to study receptor-mediated signal transduction
GABAA Receptor 1 Subunit (Gabra1) Knockout Mice: Review and New Results
, we present phenotypes observed in a GABAA receptor alpha-1 subunit (Gabra1) knockout line (KO). Our results are reviewed along with those from earlier publications on different Gabra1 mutant lines. We discovered a heightened anxiety profile in KO mice
Benzodiazepine Binding to GABAA Receptors
of) GABAA receptor subtypes can be identified. Preparation of membrane suspensions for this procedure is described in a Support Protocol, and five Alternate Protocols are provided for the identification of diazepam?sensitive GABAA receptors, the ?1?subtype
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