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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of human Pirh2 expressed in E. coli.
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, R
- 保质期:
1-2年
- 抗原来源:
Purified recombinant fragment of human Pirh2 expressed in E. coli.
- 目录编号:
252965
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
WB, IF, FC
- 浓度:
见详细说明信息
- 靶点:
Pirh2 (1H10)
- 抗体英文名:
Pirh2 (1H10) Antibody
- 抗体名:
Pirh2 (1H10) Antibody
- 规格:
0.1 ml
Pirh2 (1H10) Antibody产品详细介绍:
| 产品名称: | Pirh2 (1H10) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252965 |
| 规格: | 0.1 ml |
| 产品描述: | Pirh 2 (P53 induced RING-H2 protein) mediates E3-dependent ubiquitination and proteasomal degradation of proteins. Pirh2 has ubiquitin-protein ligase activity and binds to p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. Pirh2 is oncogenic because loss of p53 function contributes directly to malignant tumor development. Pirh2 expression decreases the level of p53, and a decrease of endogenous Pirh2 expression increases p53 levels. Pirh2 is therefore considered together with MDM2, to act as a negative regulator of p53 function. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Purified recombinant fragment of human Pirh2 expressed in E. coli. |
| 适用物种: | H, R |
| 应用范围: | WB, IF, FC |
| 应用说明: | WB: 1:500-1:2000; IF: 1:200-1:1000; FC: 1:200-1:400; |
| 别名: | RING finger and CHY zinc finger domain-containing protein 1; Androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger protein 199; Zinc finger protein 363; p53-induced RING-H2 protein; hPirh2; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; RCHY1 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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