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- MultiSciences
- 156.25 pg/mL - 10000 pg/mL
- 杭州
- 70-EK287-96
- 2026年03月25日
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- 文献和实验
- 技术资料
- 库存：
99
- 供应商：
联科生物
- 检测范围：
156.25 pg/mL - 10000 pg/mL
- 检测方法：
双抗夹心法
- 应用：
ELISA
- 适应物种：
Mouse
- 标记物：
HRP
- 样本：
血清，血浆，细胞培养上清及其他生物学样本
- 规格：
96T/48T
| 规格： | 96T | 产品价格： | ￥2650.0 |
|---|---|---|---|
| 规格： | 48T | 产品价格： | ￥1600.0 |
| 背景介绍 | 趋化因子配体2(CCL2)，又名单核细胞趋化蛋白1(MCP-1)，是CC趋化因子家族的小分子量细胞因子。CCL2通过蛋白聚糖的粘多糖侧链锚定到内皮细胞的质膜上，主要由单核细胞、巨噬细胞和树突状细胞分泌。CCL2可招募单核细胞、记忆性T细胞和树突状细胞到组织损伤或感染引起的炎症位点。
CCL2参与以单核细胞浸润为特征的一些疾病发病机制，如银屑病、类风湿性关节炎和动脉粥样硬化。CCL2参与发生在中枢神经系统的多种疾病的神经炎症过程，表现为神经元变性。 |
| 检测原理 | 本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗小鼠CCL2抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的CCL2与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中CCL2的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570-630 nm)测定吸光度值。 |
| 组分 | 包被抗CCL2/MCP-1单克隆抗体的96孔聚苯乙烯酶标板 小鼠CCL2/MCP-1冻干标准品 CCL2/MCP-1检测抗体 标准品稀释液 检测缓冲液(10×) 底物(TMB) 终止液 洗液(20×) 封板膜 |
| 分析类型 | 夹心ELISA |
| 样本类型 | 血清、血浆，细胞培养上清及其他生物学样本 |
| 板式 | 96孔板，可拆 |
| 保存 | 试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。 |
| 运输条件 | 4℃蓝冰运输 |
| 样本体积 | 20 μl |
| 灵敏度 | 20.54 pg/ml |
| 标准曲线范围 | 156.25-10000 pg/ml |
| 回收率范围 | 89 %-113 % |
| 平均回收率 | 1 |
| 板间变异系数 | 3.8 %-4.1 % |
| 板内变异系数 | 3.3 %-4.6 % |
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相关实验
)、MIllp、正常T细胞激活上调性表达因子(RANTES)、单核细胞趋化蛋白―1(MCP-1／MCAF)、MCP-2、MCP-3和1-309等；③C-X3―C亚族，只有一个成员Fractalkine；④XC亚族，目前发现有淋巴细胞趋化因子(1vmphotactin，LTN)和SCM-1日两个成员。 7．其他细胞因子 如表皮生长因子(EGF)、血小板衍生生长因子(PDGF)、成纤维细胞生长因子(FGF)、肝细胞生长因子(HGF)、胰岛素样生长因子―I(1GF-1)和IGF-Ⅱ、白血
RAT/MOUSE GROWTH HORMONE ELISA KIT
实验原理 This assay is a Sandwich ELISA based, sequentially, on: 1) capture of rat or mouse Growth Hormone molecules from samples to the wells of a microtiter plate coated by a pre-titered amount of anti-Growth Hormone
（2）LD78和Act-2分别是人的MIP-1α和NIP-1β，与小鼠源性MIP-1α和NIP-1β有很高同源性。 （3）GROα、GROβ和GROγ指基因产物。 3.趋化因子作用特点 趋化因子C-X-C和C-C亚族的生物学活性有明显的差别。C-X-C亚族中，除γIP-10、Nig和PF-4外，其余成员均具有趋化和激活中性粒细胞的活性。编码这个亚族成员的基因定位于第4号染色体长臂，氨基酸水平上的同源性在25%～90%。γIP-10主要趋化单核细胞和T细胞。C-C亚族主要趋化
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Mouse CCL2/MCP-1 ELISA Kit（小鼠趋化因子配体2/单核细胞趋化蛋白1试剂盒）
￥1600 - 2650
