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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ATP7B
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ATP7B
- 抗体英文名:
ATP7B antibody
- 抗体名:
ATP7B antibody
- 规格:
100μl
ATP7B antibody
Product Name ATP7B antibody
Catalog No PAab09849
Packing 100ul
Form liquid
Alternative Name PWD, WC1, WD, WND
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Immunogen ATP7B
Specificity Human, Mouse
Tested Application ELISA, WB, IF
Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200
IHC use
WB use
mouse liver tissue were subjected to SDS PAGE followed by western blot with PAab09849( ATP7B antibody ) at dilution of 1:1000
Protein Information
Gene ID 540
Uniprot ID P35670
Calculated MW 30 kDa
Research Area Signal Transduction, Metabolism
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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