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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
cAMP responsive element binding protein 3-like 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CREB3L2
- 抗体英文名:
anti-CREB3L2 antibody,CREB3L2 antibody
- 抗体名:
anti-CREB3L2 抗体,CREB3L2 抗体
- 规格:
100μg
CREB3L2抗体| CREB3L2 antibody
货号 PAab01964
蛋白别名 BBF2H7
蛋白介绍
Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress- induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
产品描述
anti-CREB3L2 antibody is a Rabbit Polyclonal antibody againstCREB3L2..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!)
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