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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Human FCER1A / Fc epsilon RI alpha Protein (ECD)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
100 µg/1 mg
| 规格: | 100 µg | 产品价格: | ¥3870.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥25190.0 |
蛋白名称:Human FCER1A / Fc epsilon RI alpha Protein (ECD)
蛋白构建:A DNA sequence encoding the human FCER1A (NP_001992.1) (Met1-Gln205) was expressed.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE.
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg protein as determined by the LAL method.
预测N端:Val 26
蛋白分子量:The recombinant human FCER1A consists of 180 amino acids and predicts a molecular mass of 21 kDa. As a result of glycosylation, it migrates as an approximately 42.5 KDa band in SDS-PAGE under reducing conditions.
蛋白NP号:NP_001992.1
蛋白氨基酸序列:Met1-Gln205
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Micropatterned Ligand Arrays to Study Spatial Regulation in Fc Receptor Signaling
Fc receptor signaling plays a fundamental role in immune responses. A plethora of Fc �receptors (e.g., Fc gamma, Fc-alpha, and Fc-epsilon) are expressed on different immune cells, including natural killer cells, macrophages, mast cells
,亲合力增高Kd为10-8M。IgG与Clq结合点位于CH2功能区中最后一个β折叠股318~322位氨基酸残基(Glu-x-Lys-x-Lys)。IgM倍以上。人类天然的抗A和抗B血型抗体为IgM,血型不符合引韦的输血反应发生快而且严重。 2.凝聚的IgA、IgG4和IgE等可通过替代途径活化补体。 (三)结合Fc受体 不同细胞表面具有不同Ig的Fc受体,分别用FcγR、FcεR、FcαR等来表示。当Ig与相应抗原
Capture and Qualitative Analysis of the Activated Fc Receptor Complex from Live Cells
., Saito, N., Larsson, C., Loegering, D., Weber, P.B., and Lennartz, M.R. 2002. A role for PKC‐epsilon in Fc gammaR‐mediated phagocytosis by RAW 264.7 cells. J. Cell Biol. 159:939‐944.
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