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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Zika virus(ZIKV)(strain Zika SPH2015)E/Envelope protein(His Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
20.00 µg/50.00 µg/100.00 µg
| 规格: | 20.00 µg | 产品价格: | ¥1270.0 |
|---|---|---|---|
| 规格: | 50.00 µg | 产品价格: | ¥2050.0 |
| 规格: | 100.00 µg | 产品价格: | ¥4520.0 |
蛋白名称:ZIKV Envelope蛋白, ZIKV Envelope protein
蛋白构建:A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (ALU33341.1) (Ile291-Gly694) was expressed with a polyhistidine tag at the C-terminus.
表达宿主:Baculovirus-Insect Cells
蛋白纯度:> 90 % as determined by SDS-PAGE.
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg protein as determined by the LAL method.
预测N端:Ile 291
蛋白分子量:The recombinant Zika virus (strain Zika SPH2015) E / Envelope consists of 415 amino acids and predicts a molecular mass of 45.5 kDa.
蛋白NP号:ALU33341.1
蛋白氨基酸序列:Ile291-Gly694
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验2, Niu X, et al. Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response.Emerging microbes & infections, PubMed ID: 31906823
3, Zhou J, et al. Zika virus leads to olfactory disorders in mice by targeting olfactory ensheathing cells.EBioMedicine, PubMed ID: 36739631
4, Miranda-López A, et al. Rational design and production of a chimeric antigen targeting Zika virus that induces neutralizing antibodies in mice.Vaccine, PubMed ID: 38749821
三句话读懂一篇 CNS:寒冷时食欲大增之谜;吸电子烟会增加多
Metabolism 杂志发表研究论文 Aberrant NAD+ metabolism underlies Zika virus-induced microcephaly。以多组学研究策略,揭示 ZIKV 感染导致小头症脑组织引起显著的烟酰胺腺嘌呤二核苷酸(NAD+)代谢重编程机制,以小鼠为动物模型,发现靶向干预 NAD+ 代谢路径可有效改善 ZIKV 感染所致的小头症!该研究为人类攻克寨卡病毒提供了新思路,愿该病毒早日从地球消失!图 2:来源站酷海洛3. Nature Genetics:揭示慢性肾脏病的致病
(9), 2062-2085. 【2】LANCASTER, Madeline A., et al. Cerebral organoids model human brain development and microcephaly. Nature, 2013, 501.7467: 373-379. 【3】DANG, Jason, et al. Zika virus depletes neural progenitors in human cerebral organoids through activation
哈佛学者研发新型寨卡病毒疫苗,显著降低垂直传播风险,解决有效性欠佳问题
寨卡病毒(Zika Virus, ZIKV)自 2015 年在美洲大规模流行,其感染怀孕母体后,引发腹中胎儿小头症等发育畸形。目前已有研究报道 ZIKV 疫苗在成年未怀孕小鼠、恒河猴体内的有效性, 然而因感染 ZIKV 的母体持续产生病毒血症,迄今为止仍无安全高效的 ZIKV 疫苗完全保护母体及胎儿,研发该类疫苗的难度较大。2019 年 11 月中旬,来自哈佛医学院的 Dan H. Barouch 团队在国际期刊 Cell Host & Micorbe 上发表 ZIKV 疫苗
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