Indobufen吲哚布芬,63610-08-2

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Indobufen

CAS No. : 63610-08-2

MCE 国际站：Indobufen

产品活性：Indobufen 是一种血小板聚集抑制剂。Indobufen 是一种可逆的血小板环加氧酶 (Cox) 活性抑制剂。Indobufen 抑制血栓素 A₂ (TxA₂) 合成。Indobufen 降低单核细胞中的组织因子。

研究领域：Immunology/Inflammation

作用靶点：COX

In Vitro: Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB₂ levels. Indobufen inhibits TxA₂ but not PGE₂ synthesis in LPS-stimulated monocytes. Indobufen reduces the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered.

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