产品货号:jlcR21936 英文名称 :CD163L1 中文名称 : CD163蛋白样1抗体 别 名 :C163B_HUMAN; CD163 antigen B; CD163 antigen-like 1; CD163 molecule-like 1; CD163b; CD163b antigen; CD164L1; M160; Scart1; Scavenger receptor cysteine-rich type 1 protein M160. 研究领域 :细胞生物 免疫学 抗体来源 :Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, 产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 : 154kDa 细胞定位 : 细胞膜 分泌型蛋白 性 状 : Lyophilized or Liquid 浓 度 : 1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human CD163L1:691-790/747 亚 型 : IgG 纯化方法 : affinity purified by Protein A 储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed 产品介绍 : This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Subcellular Location: Secreted and Cell membrane.
Tissue Specificity: Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.
Similarity: Contains 12 SRCR domains.
SWISS: Q9NR16
Gene ID: 283316
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.