重组猴IL-1β北京厂家

特别提示：包括重组猴IL-1β在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组猴IL-1β
英文名称：Recombinant Rhesus macaque Interleukin 1 beta
产品货号：GS4469
产品规格：2μg

分子量：Approximately 17.3kDa,a single non-glycosylated polypeptide chain containing 153 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-1beta(IL-1β)is a non-secreted proinflammatory cytokine produced mainly by activated macrophages,as well as neutrophils,epithelial cells,and endothelial cells.It possesses metabolic,physiological,haematopoietic activities,and plays one of the central roles in the regulation of the immune responses.Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties.These cytokines have a broad range of activities including,stimulation of thymocyte proliferation,by inducing IL-2 release,B-cell maturation and proliferation,mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.The mature Rhesus macaque IL1β shares 96%amino acid sequence identity with rhesus and 67%- 78%with canine,mouse and rat IL1β.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine D10.G4.1 cells is less than 10pg/ml,corresponding to a specific activity of>1.0×108 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rRhIL-1β as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS

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