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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,IHC,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
- 抗体英文名:
anti-UBE2B antibody,UBE2B antibody
- 抗体名:
anti-UBE2B 抗体,UBE2B 抗体
- 规格:
100μl
UBE2B抗体| UBE2B antibody
货号 PAab09164
蛋白别名 E2 17kDa antibody, HHR6B antibody, HR6B antibody, RAD6 homolog B antibody, RAD6B antibody, UBC2 antibody, UBE2B antibody, Ubiquitin carrier protein B antibody, Ubiquitin protein ligase B
蛋白介绍
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys- 164'. May be involved in neurite outgrowth.
产品描述
anti-UBE2B antibody is a Rabbit Polyclonal antibody againstUBE2B..
建议稀释比例
WB : 1:200-1:2000;IHC:1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human ovary tumor using PAab09164(UBE2B antibody) at dilution of 1:10
Western blot
L02 cells were subjected to SDS PAGE followed by western blot with PAab09164( UBE2B Antibody) at dilution of 1:600(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验三句话读懂一篇 CNS:扎心!赚得越少,死亡风险可能越高;何时运动都不晚,都能改善大脑功能
Transduction and Targeted Therapy 杂志发表研究论文 From tuberculosis bedside to bench: UBE2B splicing as a potential biomarker and its regulatory mechanism。 该研究开发了结核病相关 AS 生物标志物 (S100A8 -内含子-保留内含子、RPS20 -exon1 替代启动子、KIF13B-exon4 跳过外显子 (SE) 和 UBE2B-exon7-SE),证明了目标生物
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