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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
EPH receptor A7
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9WVH4
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
EPHA7
- 抗体英文名:
anti-EPHA7 antibody,EPHA7 antibody
- 抗体名:
anti-EPHA7 抗体,EPHA7 抗体
- 规格:
100μl
EPHA7抗体| EPHA7 antibody
货号 PAab02805
蛋白别名 EHK3 antibody, HEK11
蛋白介绍
Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.
产品描述
anti-EPHA7 antibody is a Rabbit Polyclonal antibody againstEPHA7..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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