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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
microtubule-associated protein tau
- 亚型:
IgG2c
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
monoclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
6个月
- 抗原来源:
Mouse
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
microtubule-associated protein tau
- 抗体英文名:
TAU antibody
- 抗体名:
TAU antibody
- 规格:
100μl
TAU antibody
Product Name TAU antibody
Catalog No PAab10118
Packing 100ul
Form liquid
Alternative Name DDPAC, FLJ31424, FTDP 17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PPND, TAU
Purification protein A+G purified
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG2c
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Immunogen microtubule-associated protein tau
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:1000 - 1:10000; IHC: 1:100 - 1:400
IHC use Immunohistochemistry of paraffin-embedded mouse brain tissue slide using PAab10118( TAU Antibody) at dilution of 1:200
WB use
U-251 cells were subjected to SDS PAGE followed by western blot with PAab10118(TAU antibody) at dilution of 1:5000
Protein Information
Gene ID 4137
Uniprot ID P10636
Calculated MW 100 kDa
Research Area Neuroscience
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文献和实验Tau 蛋白是一种微管相关蛋白,分子量 50~75 kDa,主要位于神经元轴突中,是维持骨骼神经元系统稳定性所需的重要分子。
Tau pathology refers to molecular mechanisms leading to the intracellular aggregation of abnormally modified Tau protein isoforms and to the propagation of this degenerating process along neuronal �circuitry. Tau proteins belong to the family
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人TAU 蛋白 (TAU)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 TAU 单抗包被于酶标板上,标准品和样品中的 TAU与单抗结合,加入生物素化的抗人 TAU ,形成免疫复合
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