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- 询价记录
- 文献和实验
- 技术资料
- 生长状态：
贴壁生长
- 库存：
大量
- 年限：
56 years
- 运输方式：
冻存运输
- 器官来源：
胰腺
- 细胞形态：
上皮样
- 相关疾病：
腺癌
- ATCC Number：
CRL-2172™
- 物种来源：
人
- 是否是肿瘤细胞：
1
| Designations: | SW 1990 [SW-1990, SW1990] | ||
| Depositors: | W McCombs | ||
| Biosafety Level: | 1 | ||
| Shipped: | frozen | ||
| Medium & Serum: | See Propagation | ||
| Growth Properties: | adherent | ||
| Organism: | Homo sapiens | ||
| Morphology: | epithelial |
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| Source: | Organ: pancreas Disease: adenocarcinoma Derived from metastatic site: spleen |
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| Permits/Forms: | In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location. | ||
| Restrictions: | These cells are distributed for research purposes only. The Scott and White Clinic releases the line subject to the following: 1) The cells or products derived from them must not be sold or used for commercial purposes. Nor can the cells be distributed to third parties for purpose of sale, or producing for sale, cells or their products. Commercial interests are the exclusive property of the Scott and White Clinic. 2) Any proposed commercial use of these cells or products produced by them must first be negotiated with the Scott and White Clinic, 2401 S. 31 Street, Temple, Texas 76508. Telephone (817) 774-2432 | ||
| Isolation: | Isolation date: 1978 | ||
| Tumorigenic: | Yes | ||
| Antigen Expression: | Blood Type A; Rh + | ||
| DNA Profile (STR): | Amelogenin: X CSF1PO: 10, 12 D13S317: 8, 12 D16S539: 13 D5S818: 12, 13 D7S820: 9, 10 THO1: 9.3 TPOX: 8, 9 vWA: 17 |
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| Cytogenetic Analysis: | near triploid; range = 67 to 75 | ||
| Age: | 56 years | ||
| Gender: | male | ||
| Ethnicity: | Caucasian | ||
| Comments: | The SW 1990 line was established in 1978 from a spleen metastasis of a grade II pancreatic adenocarcinoma deriving from the exocrine pancreas. The cells have a reported plating efficiency of 29%. |
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| Propagation: | ATCC complete growth medium: The base medium for this cell line is ATCC-formulated Leibovitz's L-15 Medium, Catalog No. 30-2008. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%. Temperature: 37.0°C Atmosphere: air, 100% |
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| Subculturing: | Protocol:
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| Preservation: | Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO Storage temperature: liquid nitrogen vapor phase |
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| Doubling Time: | 64 hrs | ||
| Related Products: | Recommended medium (without the additional supplements or serum described under ATCC Medium):ATCC 30-2008 recommended serum:ATCC 30-2020 |
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| References: | 23047: Kyriazis AP, et al. Establishment and characterization of human pancreatic adenocarcinoma cell line SW-1990 in tissue culture and the nude mouse. Cancer Res. 43: 4393-4401, 1983. PubMed: 6871872 | ||
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文献和实验相关实验
吾夜清心 请教：胰腺癌细胞有耐药的吗？如耐5-FU胰腺癌细胞株，耐多种药物胰腺癌细胞株 我想从逆转耐药着手，有耐药的肿瘤细胞株吗？ 谢谢:P zhujoker 胰腺癌细胞有耐药的，比如胰腺癌耐药细胞株SW1990/FU的建立、鉴定。这是采用5-氟尿嘧啶（5-FU）浓度梯度递增法建立胰腺癌耐药细胞株SW1990/FU。耐多种药物胰腺癌细胞株，耐药细胞亚株SW1990／FU和SW1990／ADM，不过好像这些耐药
[摘要] 目的 探讨阿司匹林对人γδT细胞杀伤消化道肿瘤细胞株的影响。方法 用异戊烯焦磷酸法体外扩增人外周血γδT细胞。用不同浓度的阿司匹林诱导γδT细胞和消化道肿瘤SGC-7901、SW-1990、SW-480、SW-1116、LOVO细胞株，用MTT法检测阿司匹林对这些细胞的抑制率和用乳酸脱氢酶法测定γδT细胞的杀伤活性，用流式细胞术检测诱导前后的γδT细胞和SGC-7901、SW-1990、SW-480、SW-1116和LOVO细胞凋亡百分率。结果 γδT细胞培养10天时从扩增前4.21
藤红素和 19-048 治疗后能抑制结直肠癌细胞的增殖以及降低细胞活力。为了确定雷公藤红素和 19-048 是否通过靶向 PRDX1 影响细胞氧化还原状态，作者在 SW620 和 HCT116 细胞中用 DCFH-DA 荧光探针染色检测 ROS 水平，在不同浓度的雷公藤红素和 19-048 处理后，与对照相比，细胞中的 ROS 含量急剧升高，随后检测了雷公藤红素和 19-048 对 NCM460 细胞中 ROS 水平的影响，结果表明，雷公藤红素和 19-048 对正常细胞 ROS 诱导的影响小于癌
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SW 1990
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