重组小鼠FGF-7/KGF-1现货供应

特别提示：包括重组小鼠FGF-7/KGF-1在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠FGF-7/KGF-1
英文名称：Recombinant Murine Keratinocyte Growth Factor-1/FGF-7
产品货号：GS4450
产品规格：2μg

分子量：Approximately 18.7kDa,a single,non-glycosylated polypeptide chain containing 163 amino acids.
储存条件：冷冻（-20℃）

概述

Murine KGF-1 also known as Fibroblast growth factor 7(FGF-7),is encoded by the FGF7 gene.KGF-1 only binds to the b splice form of the tyrosine kinase receptor,FGFR2b/KGFR.Affinity between KGF-1 and its receptor can be increased by heparin or heparin sulfate proteoglycan.FGF-10,also called keratinocyte growth factor 2(KGF-2),shares 51%amino acid sequence identity and similar function to KGF-1,but uses an additional receptor,FGFR2c.KGF-1 plays an important role in the regulation of embryonic development,cell proliferation and cell differentiation.KGF-1 actives on keratinocytes,and exhibits mitogenic activity for epidermal cells,but essentially no activity for fibroblasts.KGF-1 has species crossactive,murine KGF-1 shares 96%amino acid sequence identity with human and rat.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered solution in 20mMPB,pH 8.0,1MNaCl.
内毒素	Less than 1 EU/μg of rMuKGF-1/FGF-7 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT

我公司销售的重组小鼠FGF-7/KGF-1现货供应，FGF-7/KGF-1, Murine，重组小鼠Murine Keratinocyte Growth Factor-1/FGF-7，Recombinant Murine Keratinocyte Growth Factor-1/FGF-7，重组Murine Keratinocyte Growth Factor-1/FGF-7质量上佳，价格普惠，欢迎广大新老客户踊跃订购。