重组人BMP-7北京供应商

特别提示：包括重组人BMP-7在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人BMP-7
英文名称：Recombinant Human Bone Morphogenetic Protein 7
产品货号：GS4442
产品规格：2μg

分子量：Approximately 15.7kDa,a monomeric,non-glycosylated polypeptide chain containing 139 amino acids.
储存条件：冷冻（-20℃）

概述

Bone Morphogenetic Protein 7 is one of the BMPs,some of which belong to the TGF-beta superfamily(BMP2-7).There are more than thirteen BMPs have been discovered nowadays and they are involved in inducing cartilage and bone formation.BMP-7 is mainly expressed in kidney and bladder.It is also present in developing eyes,brain and ear during embryogenesis.BMP-7 also named osteogenic protein-1(OP-1)is a potent osteoinductive cytokine and plays role in osteoblast differentiation,SMAD1 production and renal development and repair.Human BMP-7 is synthesized with a signal sequence(29 a.a.),a propeptide(263 a.a.),and a growth factor domain(139 a.a.).The growth factor domain of human BMP-7 shares 98%a.a.sequence identity with mouse and rat BMP-7.

应用

1.Molecular standard(Western,ELISA)in studying secreted BMP-7;2.Preparing antibodies for BMP-7 monomer;3.Molecule standard in detecting secreted BMP-7 in reduced SDS-PAGE.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Data is not available.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 30%acetonitrile,0.1%TFA.
内毒素	Less than 1 EU/μg of rHuBMP-7 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in 10mMHAc to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	STGSKQRSQN RSKTPKNQEA LRMANVAENS SSDQRQACKK HELYVSFRDL GWQDWIIAPE GYAAYYCEGE CAFPLNSYMN ATNHAIVQTL VHFINPETVP KPCCAPTQLN AISVLYFDDS SNVILKKYRN MVVRACGCH

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