重组人SDF-1β/CXCL12β北京品牌

特别提示：包括重组人SDF-1β/CXCL12β在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人SDF-1β/CXCL12β
英文名称：Recombinant Human Stromal-Cell Derived Factor-1 beta/CXCL12β
产品货号：GS4527
产品规格：2μg

分子量：Approximately 8.5kDa,a single non-glycosylated polypeptide chain containing 72 amino acid residues.
储存条件：冷冻（-20℃）

概述

CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.It is encoded by the CXCL12 gene.In recently study,Human CXCL12 is expressed as six isoforms that differ only in the C-terminal tail.And all SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.CXCL12 is a very important factor in carcinogenesis and the neovascularisation linked to tumor progression.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20-80ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuSDF-1β/CXCL12β as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM

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