重组人PF-4/CXCL4北京品牌

特别提示：包括重组人PF-4/CXCL4在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人PF-4/CXCL4
英文名称：Recombinant Human Platelet Factor-4/CXCL4
产品货号：GS4590
产品规格：5μg

分子量：Approximately 7.8kDa,a single non-glycosylated polypeptide chain containing 70 amino acids.
储存条件：冷冻（-20℃）

概述

Platelet Factor-4(PF-4)is a small cytokine belonging to the CXC chemokine family that is also known as chemokine(C-X-C motif)ligand 4(CXCL4).The gene for human CXCL4 is located on human chromosome 4.This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin.It interacts with a splice variant of the chemokine receptor CXCR3 besides be chemotactic for neutrophils,fibroblasts and monocytes.Recombinant human CXCL4 contains 70 amino acids binds with high affinity to heparin.Specifically,Human and mouse CXCL4 share about a 60%identity.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,1.5MNaCl,pH 7.4.
内毒素	Less than 1 EU/μg of rHuPF-4/CXCL4 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES

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