关于NELL1:
Protein Kinase C-Binding Protein NELL1 is a member of EGF-like domain containing family. NELL1 is a secreted protein and contains six EGF-like domains, one TSP N-terminal (TSPN) domain and five VWFC domains. NELL1 exists as a homotrimer which may be involved in cell growth regulation and differentiation. It is reported that NELL1 enhances new blood vessel formation (angiogenesis) and controls inflammation, which are critical elements in treating severe radiation dermatitis, skeletal muscle wounds, cardiac tissue damaged by acute myocardial infarction (AMI), or heart attack.
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