- ￥700 - 8450
- MedChemExpress(MCE)
- 美国
- HY-12782T
- 2025年07月15日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1431303-72-8
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1694.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥700.0 |
| 规格： | 5 mg | 产品价格： | ￥1540.0 |
| 规格： | 10 mg | 产品价格： | ￥2450.0 |
| 规格： | 50 mg | 产品价格： | ￥8450.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Iadademstat dihydrochloride
CAS No. : 1431303-72-8
MCE 国际站：Iadademstat dihydrochloride
产品活性：Iadademstat (ORY-1001) dihydrochloride 是一种不可逆的选择性赖氨酸特异性脱甲基酶 1A (KDM1A/LSD1) 抑制剂。
研究领域：Epigenetics
作用靶点：Histone Demethylase
In Vitro: Iadademstat dihydrochloride is a KDM1A inhibitor that inactivate KDM1A by irreversible binding to the flavin adenine nucleotide (FAD) cofactor. Iadademstat has very high selectivity for KDM1A over the MAO enzymes, high selectivity over KDM1B and unrivaled subnanomolar cellular activity in differentiation and colony formation assays on mixed lineage leukemia (MLL)-translocated acute myeloid leukemia (AML) cell lines. Iadademstat provokes a time and dose-dependent induction of the Cd11b differentiation marker in MLL-AF9 cells, which interestingly preceeds changes in H3K4me2 levels. While MLL-translocated cells are especially sensitive, other acute leukemia (AL) cell lines also respond to Iadademstat.
In Vivo: Iadademstat reduces AML tumor growth in mice and rat xenografts and increases survival time in a disseminated model of T-ALL.
相关产品：Covalent Screening Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Epigenetics Compound Library | Histone Modification Research Compound Library | Anti-Cancer Compound Library | Clinical Compound Library | Covalent Screening Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Targeted Diversity Library | Highly Selective Inhibitors Library | GSK-J4 | Eicosapentaenoic Acid | IOX1 | JIB-04 | CPI-455 | Tranylcypromine hemisulfate | KDM5-C70 | SP2509 | QC6352 | GSK2879552 | GSK-LSD1 dihydrochloride | Pulrodemstat benzenesulfonate | AS8351 | Seclidemstat | KDOAM-25 citrate | Daminozide | ML324 | NCGC00244536 | Corin | GSK467 | KDM5A-IN-1 | PFI-90 | KDM2A/7A-IN-1 | L-2-Hydroxyglutaric acid disodium | Procaine | SKLB325 | Bomedemstat hydrochloride
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验疟原虫 Malaria Parasites(Plasmodium)
can be used:Quinine dihydrochloride 20 mg salt/kg base given I.V. in 5% w/v dextrose or normal saline as a once-only 4 hour infusion followed, 4 hours later, by quinine dihydrochloride 10 mg salt/kg base 4-hour infusions 8 hourly.Where a syringe pump
Measuring Antioxidant Capacity Using the ORAC and TOSC Assays
by antioxidants, and the second is the total oxyradical scavenging capacity (TOSC) assay, which measures the decrease in ethylene gas production caused by the inhibition of the thermal hydrolysis of ABAP (2,2′-Azobis(2-methyl-(propionamidine) dihydrochloride
for each d12 mm coverslip, 25 µl for square coverslip and 50µl for full size coverslip• Seal the coverslip with nail polish• Store in 4 C up to 2 weeksDAPI stock• 4’, 6-Diamidino-2-phenylindole dihydrochloride hydrate (DAPI) from Sigma (Cat# D-9542), 1 mg 1mg
技术资料暂无技术资料 索取技术资料
