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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
56973-41-2
- 规格：
1 mg/5 mg
| 规格： | 1 mg | 产品价格： | ￥1860.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥4650.0 |
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Withanolide B
CAS No. : 56973-41-2
MCE 国际站：Withanolide B
产品活性：Withanolide B 是 W. somnifera Dunal 的活性成分。Withanolide B 通过 ERK1/2 和 Wnt/β-catenin 信号通路促进 hBMSCs 的成骨分化。 Withanolide B 具有神经保护、抗关节炎、抗衰老和抗癌的作用。
研究领域：MAPK/ERK Pathway | Stem Cell/Wnt
In Vitro: Withanolide B (1-100 nM; 3-5 days) significantly increases the expression of COL1A1 and RUNX2 genes and proteins in hBMSCs.
Withanolide B (1-100 nM; 11 or 3 days) increases the formation of extracellular matrix calcium deposits and increased the activity of alkaline phosphatase (ALP).
Withanolide B (1-100 nM; 3-5 days) increases the protein expressions of p-ERK and active β-catenin of hBMSCs.
Withanolide B (10-100 μM; 48 h) reverses the Aβ42 aggregation-induced toxicy in SK-N-SH cells.
In Vivo: Withanolide B (10 mg/kg; topical administration) promotes bone healing in a rat tibial defect model.
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随机数字：78 38 69 57 91 0 37 45 66 82 65 41 组别：乙乙甲甲甲乙甲甲乙乙甲甲 现在以随机数字的奇数代表甲组，偶数代表乙组，则编号为3、4、5、7、8、11、12号分入甲组，而1、2、6、9、10号分人乙组。因两组数字不等，继续用随机方法将甲组多余的一只调整给乙组，从上面最后一随机数字41，接下去抄一个数为62，以7除之（因甲组原分配7只）得6，即把原分配在甲组的第6个甲（即11号大鼠）调入乙组。 如果甲组多两个，则接下
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