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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
CF-102; 2-Cl-IB-MECA
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
163042-96-4
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1079.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥900.0 |
| 规格： | 10 mg | 产品价格： | ￥1500.0 |
| 规格： | 25 mg | 产品价格： | ￥3000.0 |
| 规格： | 50 mg | 产品价格： | ￥4800.0 |
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Namodenoson
CAS No. : 163042-96-4
MCE 国际站：Namodenoson
产品活性：Namodenoson (CF-102) 是一个选择性的 A3 腺苷受体 (A3AR) 激动剂 (Ki=0.33 nM)，选择性分别是 A1，A2 的 2500 和 1400 倍。
研究领域：GPCR/G Protein
作用靶点：Adenosine Receptor
In Vitro: In human ADF cells of astroglial lineage, 100 nM Namodenoson (2-Cl-IB-MECA) caused a marked reorganization of the cytoskeleton, with appearance of stress fibres and numerous cell protrusions. High concentrations of Namodenoson (2-Cl-IB-MECA) directly cause influx of Ca2+.
In Vivo: Intravenous administration of 200 μg/kg Namodenoson (2-Cl-IB-MECA) resulted in a short-lasting hypotension, which was accompanied by a 50-100-fold increase in plasma histamine concentrations. Administration of a second dose of Namodenoson (2-Cl-IB-MECA) did not elicit any hemodynamic effects.
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