RPR-260243,668463-35-2

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RPR-260243

CAS No. : 668463-35-2

MCE 国际站：RPR-260243

产品活性：RPR-260243 是一种有效的 hERG 通道抑制剂，减缓了 hERG1 通道的失活和失活。经 RPR-260243 修饰的 HERG 电流被 Dofetilide 抑制 (IC₅₀=58 nM)。RPR-260243 对其他电压依赖离子通道（包括密切相关的 ERG3 K+ 通道）没有显示类似激活剂的作用。

研究领域：Membrane Transporter/Ion Channel

作用靶点：Potassium Channel

In Vitro: RPR-260243 enhances the delayed rectifier current in guinea pig myocytes but, when administered alone, has little effect on action potential parameters in these cells.

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