- ￥568 - 5100
- MedChemExpress(MCE)
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- HY-100492
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
BLU-554
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1384.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥568.0 |
| 规格： | 5 mg | 产品价格： | ￥1250.0 |
| 规格： | 10 mg | 产品价格： | ￥2000.0 |
| 规格： | 25 mg | 产品价格： | ￥3400.0 |
| 规格： | 50 mg | 产品价格： | ￥5100.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Fisogatinib
CAS No. : 1707289-21-1
MCE 国际站：Fisogatinib
产品活性：Fisogatinib (BLU-554) 是一种有效的高选择性口服的 FGFR4 抑制剂，其 IC50 值为 5 nM。Fisogatinib 在依赖 FGFR4 信号传导的肝细胞癌 (HCC) 模型中具有显着的抗肿瘤活性。
研究领域：Protein Tyrosine Kinase/RTK
作用靶点：FGFR
In Vivo: Tissue distribution of Fisogatinib (10 mg/kg; oral gavage; for 4 hours; FVB/NRj mice) in wild-type mice is as follows; tissue concentrations decreases in the order liver > kidney > small intestine > spleen > brain. The high Fisogatinib liver-to-plasma ratio suggests there is a relatively high amount of the drug being transported into the liver.
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