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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
SJ403
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
19970-45-7
- 规格:
10 mM * 1 mL/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥3231.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥2938.0 |
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SJ572403
CAS No. : 19970-45-7
MCE 国际站:SJ572403
产品活性:SJ572403 (SJ403) 是一种 p27Kip1 抑制剂。SJ572403 对 p27-KID 的 D2 子域内的特定区域具有高度特异性,Kd 值为 2.2 mM。SJ572403 可用于与内在无序蛋白(IDPs)相关疾病的研究。
研究领域:Others
作用靶点:Others
In Vitro: SJ572403 (SJ403) (3 mM) shows specific interactions with specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM.
SJ572403 (0-3 mM) modulates p27's Cdk regulatory.
SJ572403 (10 μM-3 mM) displaces p27-D2 from Cdk2/cyclin A and partially restores Cdk2 kinase activity.
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文献和实验µl of 10% ammonium persulfate to 75 ml of Gel-mix-6. Mix by inversion. Hold the nozzle of the bottle at the corner of the gel cast. Hold the gel cast at a 45o angle to the bench and pour the gel between the plates. If bubbles get trapped
, radiotherapy, heat shock, free radicals, Ca2+ and TNF etc.[45-50]. Bax is a homologous protein of Bcl-2, in the form of homopolymer or isodipolymer Bcl-2/Bax[51-54]. The ratio of Bax and Bcl-2 protein influences the apoptotic rate of cells stimulated
3B Microtubule-associated protein 2 (MAP2) (42) AAUCCUUCGUCUUUCCUCUCG primary neuronal cells Myc-induced nuclear antigen 53 (mina53) (40) 45-63 See reference HeLa, MycB MPS1 kinase (hMps1) (8) 133-155 See reference Human HeLa S3 Myeloid cell leukemia protein
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