Quantity size: 20mg ( 20mg/ML ) packaging: Liquid form
Host species:human
Product type:Immunoglobulines Antigen - human IgA
Purification Method:Purified by Protein-A affinity chromatography. purity :>90%
Tested applications: ·Use for biotechnology
Dilution method :pH 7.2 0.01 M PBS or Sterile water dilution
Please Note: Optimal dilutions should be determined by each laboratory for each application.
Storage instructions:Store at 2-4 ºCshort term ( 4-6 Month ). Aliquot and store at -20ºClong term(1-2 Years). Avoid repeated freeze / thaw cycles.
Background: IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.. . Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.