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- 详细信息
- 技术资料
- 克隆性:
多克隆
- 适应物种:
M, H, R
- 应用范围:
WB
- 抗体英文名:
Anti-VLDL-R Antibody, clone 6A6
- 抗体名:
极低密度脂蛋白受体VLDL-R抗体
- 规格:
500ul
极低密度脂蛋白受体VLDL-R抗体现货促销
Anti-VLDL-R Antibody, clone 6A6
Anti-VLDL-R Antibody, clone 6A6
重要规格表
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| M, H, R | WB | M | Purified | Monoclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | MABS25 |
| Description | Anti-VLDL-R Antibody, clone 6A6 |
| Alternate Names |
|
| Background Information | Very low-density lipoprotein receptor (VLDL-R) belongs to the low density lipoprotein receptor family. VLDL-R binds particles containing apolipoprotein E (apoE) with high affinity. This includes VLDL, which after being bound by VLDL-R is then transported into the cell via endocytosis. It also binds to Reelin, stimulating Dab1 phosphorylation and the regulation of Tau phosphorylation. VLDL-R expression has been observed at high levels in adipose tissue, brain, heart, kidney, ovary, and skeletal muscle. It is not present in the liver. Defects involving deletion of the VLDL-R sequence are thought to be the cause of VLDLR-associated cerebellar hypoplasia (VLDLRCH also known as DES), a cerebellar disorder characterized by delayed ambulation, moderate to severe mental retardation, primarily truncal ataxia. |
| Product Information | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | Purified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Applications | |
|---|---|
| Application | Anti-VLDL-R Antibody, clone 6A6 is an antibody against VLDL-R for use in WB. |
| Key Applications |
|
| Biological Information | |
|---|---|
| Immunogen | KLH-conjugated linear peptide corresponding to the C-terminus of human VLDL-R. |
| Epitope | C-terminus |
| Clone | clone 6A6 |
| Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Host | Mouse |
| Specificity | This antibody recognizes VLDL-R at the C-terminus. |
| Isotype | IgG1λ |
| Species Reactivity |
|
| Species Reactivity Note | Demonstrated to react with mouse. Predicted to react with human and rat based on 100% sequence homology. |
| Antibody Type | Monoclonal Antibody |
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极低密度脂蛋白受体VLDL-R抗体
¥4896










