极低密度脂蛋白受体VLDL-R抗体

极低密度脂蛋白受体VLDL-R抗体

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  • ¥4896
  • merck
  • MABS25
  • 进口
  • 2025年12月09日
  • WB
  • M, H, R
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    • 详细信息
    • 技术资料
    • 克隆性

      多克隆

    • 适应物种

      M, H, R

    • 应用范围

      WB

    • 抗体英文名

      Anti-VLDL-R Antibody, clone 6A6

    • 抗体名

      极低密度脂蛋白受体VLDL-R抗体

    • 规格

      500ul

    极低密度脂蛋白受体VLDL-R抗体现货促销
    Anti-VLDL-R Antibody, clone 6A6

    重要规格表

    Species Reactivity Key Applications Host Format Antibody Type
    M, H, R WB M Purified Monoclonal Antibody
    Description
    Catalogue Number MABS25
    Description Anti-VLDL-R Antibody, clone 6A6
    Alternate Names
    • very low density lipoprotein receptor
    • very low-density lipoprotein receptor
    • VLDL receptor
    Background Information Very low-density lipoprotein receptor (VLDL-R) belongs to the low density lipoprotein receptor family. VLDL-R binds particles containing apolipoprotein E (apoE) with high affinity. This includes VLDL, which after being bound by VLDL-R is then transported into the cell via endocytosis. It also binds to Reelin, stimulating Dab1 phosphorylation and the regulation of Tau phosphorylation. VLDL-R expression has been observed at high levels in adipose tissue, brain, heart, kidney, ovary, and skeletal muscle. It is not present in the liver. Defects involving deletion of the VLDL-R sequence are thought to be the cause of VLDLR-associated cerebellar hypoplasia (VLDLRCH also known as DES), a cerebellar disorder characterized by delayed ambulation, moderate to severe mental retardation, primarily truncal ataxia.
    Product Information
    Format Purified
    Control
    • Mouse fetal brain tissue lysate
    Presentation Purified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    Applications
    Application Anti-VLDL-R Antibody, clone 6A6 is an antibody against VLDL-R for use in WB.
    Key Applications
    • Western Blotting
    Biological Information
    Immunogen KLH-conjugated linear peptide corresponding to the C-terminus of human VLDL-R.
    Epitope C-terminus
    Clone clone 6A6
    Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
    Host Mouse
    Specificity This antibody recognizes VLDL-R at the C-terminus.
    Isotype IgG1λ
    Species Reactivity
    • Mouse
    • Human
    • Rat
    Species Reactivity Note Demonstrated to react with mouse. Predicted to react with human and rat based on 100% sequence homology.
    Antibody Type Monoclonal Antibody

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