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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human TFF1 protein
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
human, mouse, rat
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Rabbit
- 应用范围:
WB, IHC, IF/ICC, ELISA
- 靶点:
TFF1
- 抗体英文名:
TFF1 Polyclonal antibody
- 抗体名:
TFF1 Polyclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2200.0 |
| 规格: | 150ul | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive WB detected in | human stomach tissue, human kidney tissue, mouse stomach tissue |
| Positive IHC detected in | human stomach cancer tissue, human colon cancer tissue, human ovary tumor tissue, human stomach tissue, mouse stomach tissue, rat stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | MCF-7 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
13734-1-AP targets TFF1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, IHC, IF/ICC, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, rat |
| 免疫原 |
CatNo: Ag4541 Product name: Recombinant human TFF1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-84 aa of BC032811 Sequence: MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | trefoil factor 1 |
| 别名 | Protein pS2, Polypeptide P1.A, PNR-2, pNR 2, HP1.A |
| 计算分子量 | 84 aa, 9 kDa |
| 观测分子量 | 9-12 kDa |
| GenBank蛋白编号 | BC032811 |
| 基因名称 | TFF1 |
| Gene ID (NCBI) | 7031 |
| RRID | AB_2202853 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P04155 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TFF1 (Trefoil factor 1, formerly known as pS2) is a small-secreted protein that belongs to the family of trefoil peptides, and characterized by the presence of one to six cysteine-rich P domains. TFF1 expression is frequently lost in gastric carcinoma, probably through mechanism of DNA methylation, and it is therefore considered as a tumor suppressor gene. The function of TFF1 was first controversially considered as an oncogene in breast cancer.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | IF | J Exp Med Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.Authors - Yalong Wang |
| human | IHC | JCI Insight Resolving the difference between left-sided and right-sided colorectal cancer by single-cell sequencing.Authors - Wei Guo |
| human | IHC, WB | Bone Trefoil factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis.Authors - Chiara Spadazzi
|
| human | WB, IHC | Biomed Pharmacother Trefoil factor 1 (TFF1) is a potential prognostic biomarker with functional significance in breast cancers.Authors - Jie Yi
|
| human | WB | Aesthet Surg J Cell-Free Fat Extract Prevents Vaginal Atrophy in Ovariectomized Model Via Promoting Proliferation of Vaginal Keratinocyte and Neovascularization.Authors - Bijun Kang |
| human | IHC | BMC Med Genomics Distinctions in gastric cancer gene expression signatures derived from laser capture microdissection versus histologic macrodissection.Authors - Kim Hark Kyun HK |
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