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MAPK Antibody Array is designed for expression profiling of key proteins in MAP Kinase signaling cascades. It is suitable for total protein profiling in human cell lysates, tissue lysates, serum, or culture media. Each package contains two identical array slides for analyzing two samples, such as an untreated sample and a treatment sample.
Catalog No: SMK060
MAP KINASE (MAPK) SIGNALING ANTIBODY ARRAY
The mitogen-activated protein kinase (MAPK) Antibody Array is an ELISA based antibody array for studying MAP kinase signaling cascades. It is designed for qualitative/semi-quantitative protein expression profiling, comparing normal samples to treated or diseased samples, and identifying candidate biomarkers.
KEY FEATURES
- Qualitative/semi-quantitative protein expression profiling
- Suitable samples: cell lysates; frozen or FFPE tissue lysates; serum; culture media
- Glass based array with high specificity and low background
- Antibodies are covalently attached to 3D polymer coated glass slides
- Each antibody is printed with six replicates
- Sensitive fluorescent detection
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文献和实验相关专题 MAPK,丝裂原活化蛋白激酶(mitogen-activated protein kinases,MAPKs)是细胞内的一类丝氨酸/苏氨酸蛋白激酶。研究证实,MAPKs信号转导通路 存在于大多数细胞内,在将细胞外刺激信号转导至细胞及其核内,并引起细胞生物学反应(如细胞增殖、分化、转化及凋亡等)的过程中具有至关重要的作用。研究表明,MAPKs信号转导通路在细胞内具有生物进化的高度保守性,在低等原核细胞和高等
-activated protein kinases,MAP激酶,MAPK)链是真核生物信号传递网络中的重要途径之一,在基因表达调控和细胞质功能活动中发挥关键作用。MAPK链由3类蛋白激酶MAP3K-MAP2K-MAPK组成,通过依次磷酸化将上游信号传递至下游应答分子 。 MAPK信号通路 包括:MAP激酶(MAPK)、MAPK激酶(MEK、MKK或MAPK 激酶)和MEK激酶(MEKK、MKKK或MAPK激酶激酶)。在哺乳动物机体中,已经发现五种不同的MAPK信号转导通路。其中ERK1/2信号
相关专题 MAPK信号通路专题 Lipopolysaccharides (LPS) are major Cell wall constituents of Gram-negative bacteria that bind to LPS-binding proteins (LBP) in plasma. The LPS-LBP complex interacts with CD14 to form a ternary
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