- ￥960 - 1600
- Solarbio
- 北京
- K004453P
- 2025年07月11日
- IF ; WB
- Rabbit
- Human Mouse Rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human ACY1
- 亚型：
IgG
- 形态：
液体/冻干粉
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，SAlexa Fluor 350，SAlexa Fluor 405，SAlexa Fluor 488，SAlexa Fluor 532，SAlexa Fluor 555，SAlexa Fluor 568，SAlexa Fluor 594，SAlexa Fluor 633，SAlexa Fluor 640，SAlexa Fluor 647，SAlexa Fluor 660，SAlexa Fluor 680，SAlexa Fluor 750
- 适应物种：
Human Mouse Rat
- 保质期：
1-3年；详询
- 抗原来源：
Recombinant protein of human ACY1
- 目录编号：
K004453P
- 级别：
科研级别
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IF ; WB
- 浓度：
WB 1:500-2000. IF 1:10-100.
- 靶点：
ACY1
- 抗体英文名：
Anti-ACY1 Polyclonal Antibody
- 抗体名：
ACY-1;ACY1D;HEL-S-5
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
实验图
Western blot analysis with ACY1 antibody diluted at 1:1000;Lane: HepG2 U-251MG A431 Jurkat Mouse brain Mouse liver Mouse kidney Rat kidney Rat liver.
Immunofluorescence analysis of HeLa cell using ACY1 antibody. Blue: DAPI for nuclear staining.
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