- ￥960 - 1600
- Solarbio
- 北京
- K002206P
- 2025年07月16日
- Rabbit
- Human Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human CDKN2A
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human Mouse
- 目录编号：
K002206P
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 靶点：
CDKN2A
- 抗体英文名：
Anti-CDKN2A Polyclonal Antibody
- 抗体名：
ARF;CDK4I;CDKN2;CMM2;INK4;INK4A;MLM;MTS-1;MTS1;P14;P14ARF;P16;P16-INK4A;P16INK4;P16INK4A;P19;P19ARF;TP16
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-CDKN2A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARF;CDK4I;CDKN2;CMM2;INK4;INK4A;MLM;MTS-1;MTS1;P14;P14ARF;P16;P16-INK4A;P16INK4;P16INK4A;P19;P19ARF;TP16 |
| 稀释比例 | WB 1:200-500. IHC 1:50-100. |
| 蛋白分子量 | 17/11/14kDa |
| Gene ID | 1029 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CDKN2A |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CDKN2A |
| 亚细胞定位 | Cytoplasm Nucleus |
| Swiss Prot | P42771,Q8N726 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. |
| 应用 | WB IHC |
| 规格 | 50ul 100ul |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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