重组人泛素结合酶E2-K(UBCE2K)

特别提示：包括重组人泛素结合酶E2-K(UBCE2K)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人泛素结合酶E2-K(UBCE2K)
英文名称：Recombinant Human Ubiquitin-Conjugating Enzyme E2 K
产品货号：JN1965
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asn200在N端带有GST标签。

UBCE2K质量控制：＞95%(还原性SDS-PAGE)

UBCE2K制剂：液体

UBCE2K保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBCE2K：
Ubiquitin-Conjugating Enzyme E2 K (UBCE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBCE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBCE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBCE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBCE2K is involved in Alzheimers disease, Huntingtons disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.

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