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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海觅拓
- 规格:
10ml/6X10ML/10X10ML
| 规格: | 10ml | 产品价格: | ¥421.85 |
|---|---|---|---|
| 规格: | 6X10ML | 产品价格: | ¥1258.0 |
| 规格: | 10X10ML | 产品价格: | ¥2061.0 |
性质
| Related Categories | Adjuvant Reagents, Adjuvant emulsions, Antibody Purification and Characterization, Vaccine Adjuvants,抗体, 更多... |
| form | liquid |
| color | faintly yellow to yellow |
| storage temp. | 2-8°C |
产品描述
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Other Notes
每毫升含 0.85mL 石蜡油和 0.15mL 二缩甘露醇一油酸。
Application
Freund′s adjuvant (incomplete) lacks the Mycobacteria found in Complete Freund′s Adjuvant so it minimizes the side-effects. It is used for boost injections. It was used to emulsify antigens that are injected into animals to produce monoclonal antibodies from the antiserum.[1][2]
弗氏佐剂可用于制备免疫原的油包水乳液。由于抗原释放
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文献和实验又称水油乳化佐剂。是由J.夫罗因德(1942)所创制的、以诱发实验动物强烈免疫反应为目的的最常用佐剂。由矿物油(例如BayolF)85%同表面活性剂(例如ArlacelA)15%混合而成,称为不完全佐剂(incomplete adjuvant),再加入分枝杆菌(结核菌等)的加热死菌(0.1—1毫克/毫升)则称完全佐剂(complete adjuvant)。在实际使用时,加抗原悬浮液和等量的佐剂,搅拌后作为水油乳剂(water-in-oil emulsion)注射于皮下、脚心、腹腔
Freund’s adjuvants are water-in-mineral oil emulsions (W/O emulsions) without heat-killed mycobacteria added (Freund’s incomplete adjuvant) or with heat-killed mycobacteria added (Freund’s complete adjuvant). Freund’s adjuvants are, in a way
Adjuvant Activity of Cytokines
The activity of several potent adjuvants, including incomplete Freund’s adjuvant, CpG oligodeoxynucleotides, and alum, has been shown to be due at least in part to the induction of cytokines, including type I interferons (IFNs), IFN
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