重组人泛素结合酶E2-H(UBCE2H)

特别提示：包括重组人泛素结合酶E2-H(UBCE2H)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人泛素结合酶E2-H(UBCE2H)
英文名称：Recombinant Human Ubiquitin-Conjugating Enzyme E2 H
产品货号：JN1964
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu183在N端带有GST标签。

UBCE2H质量控制：＞95%(还原性SDS-PAGE)

UBCE2H制剂：液体

UBCE2H保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBCE2H：
Ubiquitin-Conjugating Enzyme E2 H (UBCE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBCE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBCE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

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