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Mouse Anti Human Pyridoxamine

5'-Phosphate Oxidase
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  • ¥1080 - 7500
  • Prospecbio
  • 以色列
  • ant-063
  • 2026年02月02日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      PNPO

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/100ug

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:100ug产品价格:¥7500.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-063

    SYNONYMS

    Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO, PDXPO, FLJ10535.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    Pyridoxine-5'-phosphate oxidase (PNPO) is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts.Vitamin B6 is an essential co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in the PNPO gene result in PNPO deficiency, a form of neonatal epileptic encephalopathy.

    CLONE

    PAT2C7AT.

    IMMUNOGEN

    Anti-human PNPO mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PNPO amino acids 57-261 purified from E. coli.

    IG SUBCLASS

    Mouse IgG1 heavy chain and k light chain.

    PURIFICATION METHOD

    PNPO antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

    FORMULATION

    1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

    STORAGE PROCEDURES

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

    STABILITY / SHELF LIFE

    12 months at -20°C. 1 month at 4°C.

    APPLICATIONS

    PNPO antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000.
    Recommended starting dilution is 1:1000.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Pyridoxine-5'-phosphate oxidase (PNPO) is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts.Vitamin B6 is an essential co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in the PNPO gene result in PNPO deficiency, a form of neonatal epileptic encephalopathy.

    相关实验
    • Immunohistochemistry: Mouse Anti-Human MCP-1

      . 4. Incubate the tissue section overnight at 4?C with Mouse Anti-Human MCP-1 at 10.0 μg/mL. Wash the slide twice for three minutes each. 5. Incubate the tissue section with the Envision HRP polymer kit (Dako) according to the manufacturer’s

    • Methods for the Detection of D-Amino-Acid Oxidase

      work, my colleagues and I concluded that D-amino-acid oxidase is not present in the mouse liver (13 ). This paper examines in greater detail the methods used in reaching that conclusion. 4 ). Organs, tissues, or tissue culture cells

    • Methods for the Detection of D-Amino-Acid Oxidase

      phosphate, and 1 mM EDTA, pH 7.7), 5 x Denhardt's solution ( 8 ), and 0.5% SDS] containing 20 μg/ml denatured, fragmented salmon sperm DNA. The D-amino-acid oxidase cDNA fragment amplified above by PCR was labeled with [-32P]dCTP (~110 TBq/mmol, Amersham

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    文献支持
    Mouse Anti Human Pyridoxamine 5'-Phosphate Oxidase
    ¥1080 - 7500