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Mouse Anti Human Lipopolysacch

aride-induced TNF factor
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  • ¥1080 - 7500
  • Prospecbio
  • 以色列
  • ant-443
  • 2026年02月02日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      LITAF

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/100ug

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:100ug产品价格:¥7500.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-443

    SYNONYMS

    Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, p53-induced gene 7 protein, Small integral membrane protein of lysosome/late endosome, LITAF, PIG7, SIMPLE, TP53I7, FLJ38636, MGC116698, MGC116700, MGC116701, MGC125274, MGC125275, MGC125276.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. LITAF is a lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of the LITAF gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in the LITAF gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget''s disease (EMPD).

    CLONE

    PAT5C10AT.

    IMMUNOGEN

    Anti-human LITAF mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LITAF amino acids 1-161 purified from E. coli.

    IG SUBCLASS

    Mouse IgG2b heavy chain and k light chain.

    PURIFICATION METHOD

    LITAF antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    1mg/ml containing PBS, pH-7.4, & 0.02% Sodium Azide and 10% Glycerol.

    STORAGE PROCEDURES

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

    STABILITY / SHELF LIFE

    12 months at -20°C. 1 month at 4°C.

    APPLICATIONS

    LITAF antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000. Recommended starting dilution is 1:1000.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. LITAF is a lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. 

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    • Immunohistochemistry: Mouse Anti-Human MCP-1

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    文献支持
    Mouse Anti Human Lipopolysaccharide-induced TNF factor
    ¥1080 - 7500