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Recombinant Human Family with

Sequence Similarity 84, Member B
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  • ¥1080 - 45885
  • Prospecbio
  • 以色列
  • pro-1779
  • 2026年01月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      FAM84B

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/20ug/1mg

    规格:5ug产品价格:¥1080.0
    规格:20ug产品价格:¥2415.0
    规格:1mg产品价格:¥45885.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1779

    SYNONYMS

    FAM84B, Family with Sequence Similarity 84 Member B, BCMP101, Breast Cancer Membrane-Associated Protein 101, Neurological/Sensory 2, Breast Cancer Membrane Protein 101, NSE2, Protein FAM84B, Protein NSE2.

    INTRODUCTION

    Family with Sequence Similarity 84, Member B (FAM84B) coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF interrupted CRAF/14-3-3 interactions and increased CRAF membrane localization, causing elevated MAPK and mammalian target of rapamycin (mTOR) signaling. FAM84B is an oncogene and possibly represents a new target for therapeutic intervention.

    DESCRIPTION

    FAM84B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 333 amino acids (1-310) and having a molecular mass of 36.9kDa.
    FAM84B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile filtered colorless solution.

    FORMULATION

    The FAM84B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.15M NaCl, 1mM DTT and 0.1mM PMSF.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. 
    Store, frozen at -20°C for longer periods of time. 
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 85% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S/SHHHHHH SSGLVPRGSH MGSMGNQVEK LTHLSYKEVP TADPTGVDRD DGPRIGVSYI FSNDDEDVEP QPPPQGPDGG GLPDGGDGPP PPQPQPYDPR LHEVECSVFY RDECIYQKSF APGSAALSTY TPENLLNKCK PGDLVEFVSQ AQYPHWAVYV GNFQVVHLHR LEVINSFLTD ASQGRRGRVV NDLYRYKPLS SSAVVRNALA HVGAKERELS WRNSESFAAW CRYGKREFKI GGELRIGKQP YRLQIQLSAQ RSHTLEFQSL EDLIMEKRRN DQIGRAAVLQ ELATHLHPAE PEEGDSNVAR TTPPPGRPPA PSSEEEDGEA VAH.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    FAM84B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 333 amino acids (1-310) and having a molecular mass of 36.9kDa.
    FAM84B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    相关实验
    • Sequence Similarity Searching Using the BLAST Family of Programs

      , J.D., Dubnick, M., Polymeropoulos, M.H., Xiao, H., Merril, C.R., Wu, A., Olde, B., Moreno, R.F., et al. 1991. Complementary DNA sequencing: Expressed sequence tags and human genome project. Science 252:1651‐1656

    • TRAF‐Mediated TNFR‐Family Signaling

      .    Camerini, D., Walz, G., Loenen, W.A., Borst, J., and Seed, B. 1991. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. J. Immunol. 147:3165

    • Introduction of human 14-3-3 proteins

      of their association with the G-box DNA/protein complex by a monoclonal antibody screening approach.GF14 proteins are homologous to the 14-3-3 family of mammalian proteins.Here we demonstrate that recombinant GF14 omega,one member of the Arabidopsis GF14 protein family

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    文献支持
    Recombinant Human Family with Sequence Similarity 84, Member B
    ¥1080 - 45885