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Recombinant Human Tissue Inhib

itor of Metalloprotease 4
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  • ￥1080 - 20286
  • Prospecbio
  • 以色列
  • enz-976
  • 2025年07月09日
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    上海经科化学科技有限公司
    15 年钻石会员

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    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      TIMP4

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      1ug/5ug/50ug

    规格：1ug产品价格：￥1080.0
    规格：5ug产品价格：￥2415.0
    规格：50ug产品价格：￥20286.0

    产品细节图片1

    CATALOGUE NUMBER

    ENZ-976

    SYNONYMS

    TIMP Metallopeptidase Inhibitor 4, Tissue Inhibitor Of Metalloproteinases 4, Tissue Inhibitor Of Metalloproteinase 4, TIMP-4, Metalloproteinase Inhibitor 4.

    INTRODUCTION

    Metalloproteinase inhibitor 4 (TIMP4) is a member of a family of secreted proteins which regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. The four known members of this family are TIMP1, 2, 3 and 4. TIMP4 is produced by various tissues, particularly the brain, heart, ovary and skeletal muscle. Limited studies have shown that the TIMP4 protein has a tumor suppressive effect against Wilm92s tumor, exhibiting a negative correlation with glioma malignancy and is found in breast carcinoma cells.

    DESCRIPTION

    TIMP4 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 204 amino acids (30-224 a.a.) and having a molecular mass of 23.5kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). 
    TIMP4 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

    SOURCE

    Sf9, Baculovirus cells.

    PHYSICAL APPEARANCE

    Sterile Filtered colorless solution.

    FORMULATION

    TIMP4 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 90.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    ADPCSCAPAH PQQHICHSAL VIRAKISSEK VVPASADPAD TEKMLRYEIK QIKMFKGFEK VKDVQYIYTP FDSSLCGVKL EANSQKQYLL TGQVLSDGKV FIHLCNYIEP WEDLSLVQRE SLNHHYHLNC GCQITTCYTV PCTISAPNEC LWTDWLLERK LYGYQAQHYV CMKHVDGTCS WYRGHLPLRK EFVDIVQPHH HHHH.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献

    TIMP4 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 204 amino acids (30-224 a.a.) and having a molecular mass of 23.5kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). 

    TIMP4 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
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    文献支持
    Recombinant Human Tissue Inhibitor of Metalloprotease 4
    ￥1080 - 20286