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Recombinant Human Casein Kinas

e 2 alpha 1
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  • ¥6762 - 23000
  • Prospecbio
  • 以色列
  • pka-208
  • 2026年01月09日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CSNK2A1

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      3ug/10ug/20ug

    规格:3ug产品价格:¥6762.0
    规格:10ug产品价格:¥13524.0
    规格:20ug产品价格:¥23000.0

    产品细节图片1

    CATALOGUE NUMBER

    PKA-208

    SYNONYMS

    Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2A1, CKII alpha, CSNK2A1, PKCK2, CSK21.

    INTRODUCTION

    The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.
    Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.

    DESCRIPTION

    Casein Kinase 2 alpha 1 Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 45.1 kDa.
    Casein Kinase 2 is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    CSNK2A1 is supplied in 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 500μm PMSF, 50% glycerol, pH 8.5.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. 
    Store, frozen at -20°C for longer periods of time. 
    Avoid multiple freeze-thaw cycles.

    UNIT DEFINITION

    No protease activity detectable, specific activity > 1.320 U/mg
    (1U = 1µmol/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.

    PURITY

    Greater than 99% as determined by SDS-PAGE.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Casein Kinase 2 alpha 1 Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 45.1 kDa.
    Casein Kinase 2 is purified by proprietary chromatographic techniques.

    相关实验
    • Introduction of human 14-3-3 proteins

      whose members have been shown to activate tyrosine and tryptophan hydroxylases,inhibit protein kinase C and possess phospholipase A2 activity in vitro.We have isolated and analyzed a 14-3-3 protein cDNA clone (H14-3-3)from a human fetal brain cDNA library

    • 目前已发表文章中RNAi设计的片段综述

      -6 Casein Kinase I epsilon and delta (CKI-epsilon and CKI-delta) (17)   520-538 AACUGGGGAAGAAGGGCAACC HEK

    • 【交流】目前已发表文章中RNAi设计的片段综述

      AAGGGAAAGAAGGAGGUUUCA RBL-2H3, WEHI-231, NALM-6 Bruton's tyrosine kinase (Btk) (33) NM_000061 518-536 AAGAAGCUUAAAACCUGGGAG RBL-2H3, WEHI-231, NALM-6 Casein Kinase I epsilon and delta (CKI-epsilon and CKI-delta) (17) 520-538 AACUGGGGAAGAAGGGCAACC HEK293 Caspase 1 (34

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    文献支持
    Recombinant Human Casein Kinase 2 alpha 1
    ¥6762 - 23000