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Recombinant Human Parathyroid

Hormone (7-34)
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  • ¥3650 - 14000
  • Prospecbio
  • 以色列
  • hor-266
  • 2025年12月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      PTH (7-34)

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      100ug/0.5mg/1mg

    规格:100ug产品价格:¥3650.0
    规格:0.5mg产品价格:¥9200.0
    规格:1mg产品价格:¥14000.0

     

    CATALOGUE NUMBER

    HOR-266

    SYNONYMS

    PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452.

    INTRODUCTION

    Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin.
    PTH (7-34), which is a PTH/PTHrP receptor antagonist, can stimulate hair growth and epidermal proliferation in mice.

    DESCRIPTION

    Parathyroid Hormone Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 28 amino acids and having a molecular mass of 3380 Dalton.
    The PTH is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    The protein (1 mg/ml) was lyophilized after extensive dialyses against 20mM PBS pH-7.0 and 150mM NaCl.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized PTH in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Lyophilized Parathyrin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PTH should be stored at 4°C between 2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 97.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    LMHNLGKHLN SMERVEWLRK KLQDVHNF.

    BIOLOGICAL ACTIVITY

    The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 10,000 Units/mg.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献

    Parathyroid Hormone Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 28 amino acids and having a molecular mass of 3380 Dalton.
    The PTH is purified by proprietary chromatographic techniques.

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    Recombinant Human Parathyroid Hormone (7-34)
    ¥3650 - 14000