- ￥180 - 400
- Elabscience
- 湖北武汉
- E-AB-F1129A
- 2025年10月22日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse IgG1, κ
- 形态：
液体
- 保存条件：
This product can be stored at 2-8°C for 12 months. Do not freeze.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Mouse
- 应用范围：
FCM
- 抗体英文名：
Purified Anti-Human CD279/PD-1 Antibody[J116]_货号:E-AB-F1129A
- 抗体名：
Purified Anti-Human CD279/PD-1 Antibody流式抗体[J116]_货号:E-AB-F1129A
- 规格：
100μg/25μg
| 规格： | 100μg | 产品价格： | ￥400.0 |
|---|---|---|---|
| 规格： | 25μg | 产品价格： | ￥180.0 |
Purified Anti-Human CD279/PD-1 Antibody[J116]
| Alternate Names |
Programmed Death-1, PD-1
|
| Cellular Localization |
Cell membrane
|
| Clone No | |
| Isotype |
Mouse IgG1, κ
|
| Leadtime |
咨询
|
| Verified Samples | Verified Samples in FCM: Molt-4 |
| Dilution |
FCM 2 μg/mL(0.5×106-1×106 cells)
|
| Background |
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
|
| Immunogen | Recombinant Human CD279 protein |
| Abbre |
CD279
|
| Swissprot |
Q15116
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Purification Method |
>98%, Protein A/G purified
|
| Applications | |
| Research Areas | Cancer Biomarkers;Immunology;Inhibitory Molecules |
| Concentration |
≥ 1 mg/mL
|
| Conjugation |
Unconjugated
|
| Storage Buffer |
PBS, pH 7.2. Contains 0.05% proclin 300.
|
| Storage |
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
|
| Expiration Date |
12个月
|
| Shipping |
Ice bag
|
| Gene ID |
5133
|
Purified Anti-Human CD279/PD-1 Antibody[J116]Elabscience®提供8000+经过实验验证的高品质一抗，主要包括： 流式抗体、 单抗、 多抗、 重组抗体、 内参/标签抗体、 乙酰化/磷酸化/甲基化抗体、 磁珠/凝胶偶连抗体、 病毒抗体等。
Purified Anti-Human CD279/PD-1 Antibody[J116]This product can be stored at 2-8°C for 12 months. Do not freeze.
Purified Anti-Human CD279/PD-1 Antibody[J116]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验ATP protects anti-PD-1/radiation-induced cardiac dysfunction by inhibiting anti-PD-1 exacerbated cardiomyocyte apoptosis, and improving autophagic flux.
IF:4
Journal:Heliyon
DOI:10.1016/j.heliyon.2023.e20660
To fix, 1/10 volume of 37 formaldehyde is added to the culture, which is shaken for a further 40 minutes at room temperature. Cells are then recovered by centrifugation at 1400 X g for 2 minutes, and washed (i.e. gently resuspended then recovered
. The antibody is purified, conjugated with a bifunctional chelator for labeling with a radiometal, labeled with the positron-emitting radionuclide 64 Cu, and injected into mice for microPET studies. Mice with DSS-induced colitis were found to have higher uptake
of 0.75 to 1. To fix, 1/10 volume of 37% formaldehyde is added to the culture, which is shaken for a further 40 minutes at room temperature. Cells are then recovered by centrifugation at 1400 X g for 2 minutes, and washed (i.e. gently resuspended
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