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- 文献和实验
- 技术资料
- 亚型:
Armenian Hamster IgG
- 形态:
液体
- 保存条件:
This product can be stored at 2-8°C for 12 months. Do not freeze.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Mouse
- 保质期:
12个月
- 目录编号:
E-AB-F1124A
- 级别:
科研
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 宿主:
Armenian Hamster
- 应用范围:
FCM
- 抗体英文名:
Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5]_货号:E-AB-F1124A
- 抗体名:
Purified Anti-Mouse TCR γ/δ Antibody流式抗体[UC7-13D5]_货号:E-AB-F1124A
- 规格:
100μg/25μg
| 规格: | 100μg | 产品价格: | ¥640.0 |
|---|---|---|---|
| 规格: | 25μg | 产品价格: | ¥288.0 |

Purified Anti-Mouse TCR γ/δ 抗体流式抗体[UC7-13D5]产品名称:Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5], 货号:E-AB-F1124A
| 产品描述: | T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo. |
| Alternate Names | TCR-γ/δ; γ/δ TCR; |
| Gene ID | 110066,110067 |
| Clone No | UC7-13D5 |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Application | FCM |
| 同种型 | Armenian Hamster IgG |
| 同种型 Control | Purified Armenian Hamster IgG 同种型 Control[PIP] |
| Conjugation | Unconjugated |
| 储存方法 缓冲 | Phosphate 缓冲ed solution, pH 7.2, containing 0.09% sodium azide. |
| 储存方法 | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Expiration date | 12个月 |
| Shipping | 冰袋 |

Purified Anti-Mouse TCR γ/δ 抗体流式抗体[UC7-13D5]labscience®拥有先进的单抗,多抗和流式抗体开发技术平台,提供8500+高品质 抗体, 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证,包含 流式细胞术(Flow Cytometry)、 免疫印迹(WB)、 免疫组化(IHC/ICC)、 免疫(共)沉淀(IP/Co-IP)、 免疫荧光(IF) 等实验。抗体产品涉及多种生命科学研究领域,包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类,以保障并加快您的研究进程
This product can be stored at 2-8°C for 12 months. Do not freeze.Purified Anti-Mouse TCR γ/δ 抗体流式抗体[UC7-13D5]产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验【进展|热点】Immunity: γδ T细胞抑制调节性T细胞
γδ T细胞抑制调节性T细胞 文章出处:γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism. Immunity. 2010. 33:351-363 主要内容: T细胞根据其TCR链的不同可以分为αβ T细胞和γδ T细胞两类,前者是经典的T细胞,我们常规提到的T细胞指的就是αβ T细胞。γδ
Differentiation of Mouse Thymocytes in Fetal Thymus Organ Culture
.g., CD4+ T cells vs CD8+ T cells, and TCR-αβ+ T cells vs TCR-γδ+ T cells, 2. clonal selection, e.g., positive selection of useful T-cell clones and negative selection of harmful T-cell clones
细胞的抗原表达模式也存在差异,研究中需结合组织特异性合理搭配抗体。 Mouse CD3,CD3e和CD3复合体 CD3与CD3e是流式细胞术中检测小鼠总T细胞群的首xuan标志物,适用于绝大多数实验品系。它们广泛表达于所有T细胞亚群表面(涵盖αβTCR和γδTCR),能够实现对T细胞的全面鉴定。需要特别注意的是,在某些基因修饰小鼠模型中(例如TCR敲除模型),由于基因层面的改变,CD3ε链的表达可能会受到限制或出现异常。在这种情况下,单独使用针对CD3e的抗体可能导致T细胞漏检。因此,建议改用识别
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