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- E-AB-F1045C
- 2025年07月16日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse IgG2a, κ
- 形态：
液体
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 克隆性：
Monoclonal
- 标记物：
FITC
- 适应物种：
Human
- 保质期：
12个月
- 目录编号：
E-AB-F1045C
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Mouse
- 应用范围：
FCM
- 抗体英文名：
FITC Anti-Human CD20 Antibody[BCA/B20]_货号:E-AB-F1045C
- 抗体名：
FITC Anti-Human CD20 Antibody流式抗体[BCA/B20]_货号:E-AB-F1045C
- 规格：
100Tests/20Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1440.0 |
|---|---|---|---|
| 规格： | 20Tests | 产品价格： | ￥480.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2304.0 |
货号：E-AB-F1045C
| Background |
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
|
| Alternate Names |
B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
|
| Swissprot |
P11836
|
| Gene ID |
931
|
| Clone No |
BCA/B20
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Application |
FCM
|
| Isotype |
Mouse IgG2a, κ
|
| Isotype Control |
FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
|
| Conjugation |
FITC
|
| Conjugation Information |
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献详情查看>>>>
membrane, creating a structure similar to an ion channel Delivers early signal in B cell activation, allowing resting B cells to respond to later antigens Rituximab is a chimeric murine-human anti-CD20 antibody used for treatment of B cell
Raji细胞在4度下孵育1小时，2000g，4度离心10min，弃上清液，PBS洗三次，将细胞重悬于20ug，30ul的抗CD20 Fab或F（ab）2片段溶液，4度放置1小时，2000g，4度离心10min，弃上清液，PBS洗三次，将细胞重悬于30ul的工作液羊抗鼠IgG-FITC溶液，4度放置30min，2000g离心10min，弃上清液，PBS洗三次，FACS测定HI47结合Raji细胞的阳性率。8、Fab和F（ab）2对Raji、Daudi细胞毒作用按1104细胞/孔接种96孔培养板，分别加
of a mouse-human chimeric monoclonal antibody to Cd20 with potent Fc-dependent biologic activity. J.Immunol.，1987，139：3521[4]Press ow，Farr AG，Borroz KI，et al. Endocytosis and degradation of monoclonal antibodies targeting human B-celll malignancies. Cancer
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