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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant protein encompassing a sequence within the center region of human Purine nucleoside phosphorylase. The exact sequence is proprietary.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX117364
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, ICC/IF, IHC
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
Purine nucleoside phosphorylase
- 抗体英文名:
Purine nucleoside phosphorylase antibody
- 抗体名:
Purine nucleoside phosphorylase 抗体
- 规格:
100 μl/25 μl
| 规格: | 100 μl | 产品价格: | ¥4000.0 |
|---|---|---|---|
| 规格: | 25 μl | 产品价格: | ¥1700.0 |
Immunofluorescence analysis of methanol-fixed HeLa, using Nucleoside phosphorylase(GTX117364) antibody at 1:500 dilution.
Sample (30 ug of whole cell lysate)
A: Raji
12% SDS PAGE
GTX117364 diluted at 1:1000
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文献和实验Garcia-Esparcia P et al., Neuropathol Appl Neurobiol 2015 (PMID:25597950)
Wang H et al., Am J Cancer Res 2022 (PMID:35141027)
以嘌呤核为碱基部分的核苷的总称。把含有腺嘌呤、鸟嘌呤和次黄嘌呤( hypoxanthine)的分别称为腺嘌呤核苷(腺苷)、鸟嘌呤核苷(鸟苷)和次黄嘌呤核苷。
核苷磷酸化酶 nucleoside phosphorylase
以次黄苷 磷酸次黄嘌呤 核糖 -1-磷酸的方式,参与将核苷加磷酸分解成五碳糖磷酸反应的酶之总称。已知有几种对底物的特异性不同,如嘌呤核苷磷酸化酶( EC2. 4. 2. 1)对鸟苷、脱氧鸟苷、次黄苷、脱氧次黄苷具有作用,它存在于脾、肺、肝、心肌、红血球、酵母中,小肠和血液中也有少量存在。另外已知嘧啶核苷磷酸化酶是对尿苷和胸腺苷分别具有特异性的酶。推测主要是分解核苷或具有供给合成其它核苷所需的核糖磷酸的作用。
Tumor Sensitization to Purine Analogs by E. coli PNP
This chapter describes an approach to destroying malignant cells by effectively changing the tumor phenotype through the delivery of Escherichia coli purine nucleo-side phosphorylase (PNP). In the presence of nucleoside prodrugs
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