- ￥5600
- GeneTex
- 美国
- GTX11189
- 2025年07月05日
- WB, ELISA, IHC
- Mouse
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein containing aa1-213 of human Von Hippel-Lindau Protein (vHL). Epitope: aa1-54.
- 亚型：
IgG1
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX11189
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Mouse
- 应用范围：
WB, ELISA, IHC
- 浓度：
Batch dependent (Please refer to the vial label for the specific concentration.)
- 靶点：
Does not recognize the truncated form of VHL protein.
- 抗体英文名：
Von Hippel Lindau antibody [3F391]
- 抗体名：
Von Hippel Lindau 抗体 [3F391]
- 规格：
250 μl
WB analysis of mouse cell lysate using GTX11189 Von Hippel Lindau antibody [3F391].
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文献和实验Jatta K et al., J Clin Pathol 2009 (PMID:18818266)
Molecular Analysis of the von Hippel-Lindau Disease Gene
Von Hippel-Lindau (VHL) disease is an autosomal dominant disorder that predisposes the affected individual to develop characteristic tumors. These include CNS hemangioblastoma, retinal angiomas, endolymphatic sac tumors, pancreatic cysts
Polymerase Chain Reaction Detection of DNA Sequence Deletions
to disable tumor suppression (1 ). As might be expected, the effect of “two hits” on tumor-suppressor gene integrity—e.g., deletion of one allele and mutation of the remaining allele—would disable the gene from encoding gene product. The von Hippel-Lindau
Transcriptional Regulation of Genes via Hypoxia-Inducible Factor
Hypoxia-inducible factor (HIF) is the principal transcription factor that regulates adaptive physiologic responses to compromised oxygen tension. von Hippel–Lindau (VHL) tumor-suppressor protein binds and ubiquitylates the catalytic α subunit
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