- ￥5300
- GeneTex
- 美国
- GTX86902
- 2025年07月07日
- WB, IHC-P
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from human Aggrecan (320-369).
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX86902
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, IHC-P
- 浓度：
Batch dependent (Please refer to the vial label for the specific concentration.)
- 靶点：
Aggrecan (cleaved Asp369) antibody detects endogenous levels of fragment of activated Aggrecan resulting from cleavage adjacent to Asp369.
- 抗体英文名：
Aggrecan (cleaved Asp369) antibody
- 抗体名：
Aggrecan (cleaved Asp369) 抗体
- 规格：
100 μg
IHC-P analysis of human lung carcinoma tissue using GTX86902 Aggrecan (cleaved Asp369) antibody. The picture on the right is blocked with the synthesized peptide.
WB analysis of Jurkat cells treated with Etoposide 25uM (60mins) lysate using GTX86902 Aggrecan (cleaved Asp369) antibody. The lane on the right is blocked with the synthesized peptide.
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文献和实验Neoepitope Antibodies Against MMP-Cleaved and Aggrecanase-Cleaved Aggrecan
Neoepitope antibodies recognize the newly created N or C terminus of protein degradation products but fail to recognize the same sequence of amino acids present in intact or undigested protein. Aggrecan neoepitope antibodies have been pivotal
Antibodies to MMP-Cleaved Aggrecan
internally as part of the intact protein. This approach has been extremely successful for detecting MMP-derived fragments of aggrecan (the large cartilage proteoglycan) (1 –5 ) and collagen (6 ), since aggrecan and collagen are abundant in cartilage matrix
Proteoglycan Aggrecan-Induced Arthritis: A Murine Autoimmune Model of Rheumatoid Arthritis
. The chapter presents (a) methodological details on how to purify cartilage proteoglycan aggrecan by cesium chloride gradient centrifugation; (b) substitution of this highly purified antigenic/arthritogenic material with a crude cartilage extract obtained
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