重组人THOP1

特别提示：包括重组人THOP1在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人THOP1
英文名称：Recombinant Human Thimet Oligopeptidase
产品货号：JN1668
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Lys2-Cys689在C端含有His标签。

THOP1质量控制：＞95%(还原性SDS-PAGE)

THOP1制剂：液体

THOP1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于THOP1：
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3 and a small residue at P1 in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

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