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- Sino Biological
- 北京
- 40017-VNAHC
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Influenza A H3N2 Neuraminidase / NA (Active)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
800.00 U
蛋白名称：Neuraminidase/NA蛋白, Neuraminidase/NA protein
蛋白构建：A DNA sequence encoding the Influenza A virus (A/Babol/36/2005 (H3N2)) neuraminidase (ACN50232.1) (His 36-Pro 459) was expressed, the cell lysates are collected, and bio-activity was tested.
表达宿主：HEK293 Cells
蛋白纯度：0
蛋白活性：Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid. The specific activity is > 800 U. One unit is defined as the amount of enzyme required to cleave 1 nmole of 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid per minute at pH 7.5 at 37℃.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：0
蛋白分子量：The influenza H3N2 virus Neuraminidase comprises 424 amino acids.
蛋白NP号：ACN50232.1
蛋白氨基酸序列：His36-Pro459
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Zhang J, et al. A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.Journal of enzyme inhibition and medicinal chemistry, PubMed ID: 37955306
circulating globally. This chapter describes the fluorescent neuraminidase (NA) inhibition (NI) assay, a functional method used for assessing influenza virus susceptibility to NAIs. The IC50 (drug concentration needed to reduce the NA enzymatic activity by 50
PCR for the Detection of Influenza Viruses in Clinical Material
). Influenza A viruses are further divided into subtypes H1N1, H2N2 and H3N2, based on differences in the hemagglutinin (HA) and neuraminidase (NA) genes. The ability of influenza viruses to undergo antigenic change in HA and NA enables the virus to evade
Genetic Engineering of Live Attenuated Influenza Viruses
vaccine strain is a reassortant virus that contains the hemagglutinin (HA) and neuraminidase (NA) gene segments from a wild-type influenza virus and the six internal protein gene segments from a master donor virus (MDV) of either cold-adapted A/Ann Arbor
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